Note: The job is a remote job and is open to candidates in USA. Amylyx Pharmaceuticals is a clinical-stage company focused on treating diseases with high unmet needs. The Senior Director, Trade & Channel Operations will be responsible for building the U.S. distribution and channel model in preparation for a commercial launch, architecting the distribution strategy, and ensuring operational alignment across various functions.
Responsibilities
- Design and build Amylyx’s U.S. distribution model across specialty pharmacy, specialty distributor, and 3PL channels to support product launch
- Lead contracting strategy for specialty pharmacies and distributors, including negotiating distribution and service agreements, fee schedules, data requirements, and service levels
- Integrate distribution channels with service programs and field initiatives to enable a seamless customer experience
- Collaborate with Supply Chain and Finance to support 3PL operations, including order‑to‑cash processes, inventory management, data exchange, shipping, returns, and chargeback management
- Establish and manage noncommercial and free‑goods pharmacy operations
- Forecast and model channel performance, assess specialty pharmacy throughput, and provide recommendations to ensure timely, reliable patient access
- Develop distribution analytics including inventory visibility, service metrics, dispense data, time to therapy, and partner scorecards; lead specialty pharmacy QBRs
- Partner cross‑functionally with Supply Chain, Quality, Compliance, Legal, Finance, Patient Services, and Commercial Operations to ensure operational alignment and launch readiness
- Serve as a senior leader within Market Access, contributing to launch planning, forecasting, patient access workflows, and overall distribution strategy
- Continuously optimize post‑launch distribution operations by driving root‑cause remediation, vendor KPI management, and process improvements informed by field and service feedback
Skills
- Bachelor's degree required
- 12+ years of experience in biopharmaceutical trade and distribution, including leadership of specialty pharmacy and distributor channel networks
- Prior product launch experience in the US market
- Experience designing and implementing channel strategies for product launches
- Proven ability to assess, manage, and influence channel partner performance to contractual expectations
- Hands‑on experience with 3PL operations, serialization, state licensing, and compliant distribution processes
- Demonstrated strength in contract negotiation, vendor management, and commercial channel operations
- Deep understanding of payer reimbursement, hub/patient support integration, channel economics, and order‑to‑cash workflows
- Proven leadership experience, including managing large pharmaceutical vendors, with demonstrated people management skills
- Excellent communication, vendor management, analytical, and project execution capabilities
Company Overview
Amylyx Pharmaceuticals specializes in providing solutions for Alzheimer’s and other diseases of the brain. It was founded in 2014, and is headquartered in Cambridge, Massachusetts, USA, with a workforce of 51-200 employees. Its website is http://amylyx.com.