Note: The job is a remote job and is open to candidates in USA. Natera is a global leader in cell-free DNA testing, dedicated to oncology, women’s health, and organ health. They are seeking a Senior Bioinformatics Scientist to lead the architecture, development, and automation of high-throughput genomic pipelines, focusing on building production-grade software tools for analyzing next-generation sequencing data.
Responsibilities
• Analyze complex genomic datasets leveraging scaled in-house pipelines, partnering cross-functionally with wet-lab scientists and statisticians to rapidly deliver data-driven answers to critical research goals
• Architect, build, and deploy automated analysis pipelines for diagnostic tests, integrating robust capabilities for fusion detection, variant calling, and automated quality control metrics
• Engineer novel genomic analysis tools and proactively identify optimization pathways to enhance pipeline accuracy and efficiency
• Participate in code reviews, technical documentation, and the continuous improvement of core computational workflows
• Coordinate directly with downstream infrastructure teams to ensure R&D tools scale efficiently into production systems
Skills
• Ph.D. or Master's degree with a minimum of 5 years of professional experience in Bioinformatics, Computer Science, Engineering, Biochemistry, or a related quantitative field
• Deep theoretical and practical understanding of high-throughput DNA sequence data analysis, including mapping, sequence alignment, and variant calling workflows
• Advanced understanding of data structures, algorithm design, and computational complexity
• Strong software engineering proficiency in Java or C++ within a professional production environment
• Demonstrated scripting capability in Python or Perl for data manipulation, automation, and rapid prototyping
• Deep expertise navigating Linux environments, utilizing command-line tools, and writing efficient shell scripts
• Demonstrated technical autonomy and rigorous data discipline when troubleshooting high-complexity algorithmic challenges
• Excellent communication skills with a proven track record of explaining computational results clearly to cross-functional stakeholders
• Prior experience working with relational databases, particularly MySQL, is highly desirable
Benefits
• Comprehensive medical, dental, vision, life and disability plans for eligible employees and their dependents
• Natera employees and their immediate families receive free testing in addition to fertility care benefits
• Pregnancy and baby bonding leave
• 401k benefits
• Commuter benefits
• Generous employee referral program
Company Overview
• Natera specializes in cell-free DNA testing to provide a more targeted interventions to oncology, women's health, and organ health. It was founded in 2004, and is headquartered in San Carlos, California, USA, with a workforce of 5001-10000 employees. Its website is https://www.natera.com/.
Company H1B Sponsorship
• Natera has a track record of offering H1B sponsorships, with 6 in 2026, 90 in 2025, 72 in 2024, 37 in 2023, 71 in 2022, 64 in 2021, 40 in 2020. Please note that this does not guarantee sponsorship for this specific role.
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